Isaac has survived three Necromorph epidemics, so when someone else does that and lives to tell the tale like Isaac did then you let me know. I truly believe that Isaac is alive and that the ending *spoiler for some* isn't just a random voice recording. Isaac is the only one who knows about the brother moons, and because he defeated one, his life time mission must be to save earth from the other three brother moons.
Aside from getting stabbed in the face, puked at, confronted and eaten by leviathans only to escape, being burned, sucked out into space, forced to fly a hundred miles an hour through space, the constant dead bodies, the constant traitors, locked up in a mental institute, shot, chased by Unitoligists, crushed, chased by regenerating Necromorphs, false illusions from the markers, destroying markers, and so much more, Isaac is pretty amazing.
Yeah, I would support Isaac under the conditions that he went through and the fact that I would easily follow his example of smashing things to death with my feet, in order to survive!